News, Stories and Updates From the World of Sleep
SomnusNooze Topics: Research
Raising Awareness of the Underpinnings of Hypersomnia
Awareness of disease means different things to different people. One’s awareness takes origin in experiences and goals, both personal and professional. Diversity in awareness therefore comprises our community of people who have hypersomnia, their... read >
GABA and Histamine Work Together to Control Wakefulness
New research on genetically altered mice helps to untangle the complex interactions of GABA with brain systems necessary for sustaining wakefulness. Histamine Nerve cells (also known as neurons) in a specific part of the brain, called the... read >
Antibiotic May Decrease EDS in GABA-Related Hypersomnia
A study of clarithromycin in the treatment of GABA-related hypersomnia indicates that this drug may be effective in some patients with idiopathic hypersomnia (IH), narcolepsy without cataplexy, and subjective hypersomnia. Background The US Food and... read >
Share Your Journey | My Way of Saying That Research on IH Matters
The day a doctor finally took me seriously when I told him about always being tired, oversleeping almost every day, and generally walking through life in a sleepy fog was one of the best days of my life. I wasn't lazy! I wasn't alone! There were other... read >
It’s a Fine Line Between Type 2 Narcolepsy and Idiopathic Hypersomnia… and It’s Getting Even Finer
Researchers have provided more evidence that narcolepsy without cataplexy (Nw/oC ) and idiopathic hypersomnia (IH) without long sleep time (LST) look more alike on testing than do narcolepsy with cataplexy (NwC) and Nw/oC. This research was completed... read >
Emory Team to Receive Grant to More Fully Understand and Release the Parking Brake!
The Hypersomnia Foundation congratulates Dr. David Rye and the team at Emory University on their receipt of a 4-year award for nearly $3 million in total costs from the National Institute of Neurological Disorders and Stroke to study the biologic basis of... read >
Continuing to Unravel the Genetic Mystery of Narcolepsy
Dr. Toyoda and his colleagues in Japan have described new susceptibility genes--CCR1 and CCR3--for type 1 narcolepsy. Background Type 1 narcolepsy (also called narcolepsy with cataplexy) is believed to be the result of a combination of genetic and... read >
New Findings in a Large Well-defined Group of People with KLS
Background Kleine Levin syndrome (KLS) is a neuropsychiatric disease that affects about 1 in a million people. Symptoms include hypersomnia, confusion, derealization, hypersexuality, megaphagia, altered mood, and hallucinations that occur during... read >
First Industry-Sponsored Clinical Trial of a Treatment for Idiopathic Hypersomnia and Narcolepsy without cataplexy
NeuroTrials, Inc., has begun recruiting people to take part in the testing of a new treatment for idiopathic hypersomnia and narcolepsy without cataplexy. This small phase 1 study will test the safety and efficacy of a drug that is taken by mouth and... read >
How Long Does It Take for Sodium Oxybate to Work?
Background According to the Narcolepsy Network, although it affects more than 200,000 people in the U.S., narcolepsy is estimated to be undiagnosed or untreated in 75% of people with the disorder. This lack of recognition leads to delays in effective... read >