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Does Modafinil Improve Sleepiness in People with IH without Long Sleep Time?

Background In Europe, modafinil used to be available as a treatment for the excessive daytime sleepiness (EDS) associated with idiopathic hypersomnia (IH). However, in 2010, the European Medicines Agency (EMA, the equivalent of the Food and Drug Administration in the United States) changed the labeling, and...

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Summary of Research into Clarithromycin as a Hypersomnia Treatment

GABA is known to promote sleep and decreased consciousness, and many patients with CNS hypersomnia have been found to have endogenous GABA-A receptor hyper-reactivity.  Flumazenil, a known GABA-A antagonist, has been shown to reduce symptoms in these patients, but its use may be impractical; therefore,...

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Idiopathic Hypersomnia Symposium at the World Association of Sleep Medicine Meeting

A symposium entitled, “Idiopathic Hypersomnia: Past, Present and Future,” and co-chaired by Drs. Michel Billiard (Montpellier, France) and Sona Nevsimalova (Charles University, Prague, Czech Republic), took place at the World Association of Sleep Medicine (WASM) biannual conference in Valencia, Spain, on October 2, 2013. Approximately 130...

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