News, Stories and Updates From the World of Sleep
SomnusNooze Topics: Research

Can Actigraphy Help to Differentiate People with Narcolepsy from People with Idiopathic Hypersomnia?
Why is this study important? Type 1 narcolepsy (T1N) and idiopathic hypersomnia (IH) are both disorders of central hypersomnolence. Even though the International Classification of Sleep Disorders, third edition, includes a finding of 11 hours of sleep... read >

Hypocretin Level as a Biomarker in KLS
Background Kleine-Levin syndrome (KLS) is a rare disorder in which affected people experience episodes at least once per year during which they sleep for at least 11 hours out of every day (but often for days at a time), eat excessively (megaphagia),... read >

Does Modafinil Improve Sleepiness in People With IH Without Long Sleep Time?
Background In Europe, modafinil used to be available as a treatment for the excessive daytime sleepiness (EDS) associated with idiopathic hypersomnia (IH). However, in 2010, the European Medicines Agency (EMA, the equivalent of the Food and Drug... read >

Summary of Research into Clarithromycin as a Hypersomnia Treatment
GABA is known to promote sleep and decreased consciousness, and many patients with CNS hypersomnia have been found to have endogenous GABA-A receptor hyper-reactivity. Flumazenil, a known GABA-A antagonist, has been shown to reduce symptoms in these... read >
Idiopathic Hypersomnia Symposium at the World Association of Sleep Medicine Meeting
A symposium entitled, “Idiopathic Hypersomnia: Past, Present and Future,” and co-chaired by Drs. Michel Billiard (Montpellier, France) and Sona Nevsimalova (Charles University, Prague, Czech Republic), took place at the World Association of Sleep... read >
Emory Researchers Announce Discovery of Substance That May Be Linked to Excessive Sleeping
In a paper published in the November 21, 2012, edition of Science Translational Medicine, Dr. David Rye and a team of researchers from Emory University announced their discovery of a substance in the cerebrospinal fluid of 32 people with idiopathic... read >
Emory Magazine Features ‘Sleeping Beauty’ Case & Hope for a Cure
Emory Magazine features story of Anna, a 32-year-old attorney, who could do nothing to quench her insatiable need for sleep, even when she slept for 57 hours straight. Follow Anna’s journey for help, which led her to the Emory Healthcare Sleep Program... read >