All Hypersomnias

February 19, 2019

What is GABA? What role does it play in sleep? And is GABA activity increased by something in the cerebrospinal fluid of people with hypersomnia? We are very pleased to present Part 2 of a new two-part series by neuroscientist Amanda Freeman, PhD, of Emory...

January 15, 2019

In All Hypersomnias, Hypersomnias, Idiopathic Hypersomnia, Kleine-Levin Syndrome, Narcolepsy, Other Hypersomnias, Research, Videos

By Hypersomnia Foundation

What Is GABA? How Does It Affect Hypersomnia? A New Video Series Explains!

Amanda Freeman, PhD What is GABAA? And how does it affect hypersomnia? We are very pleased to present a two-part video series by neuroscientist Amanda Freeman, PhD, of Emory University, which describes, in layman’s terms, exactly how y-aminobutyric acid, better known as GABA, affects sleep....

December 18, 2018

In All Hypersomnias, Ask the Doctor, Hypersomnias, Idiopathic Hypersomnia, Kleine-Levin Syndrome, Narcolepsy, Other Hypersomnias

By Hypersomnia Foundation

Ask the Doctor: Do Women’s Hormones Affect Their Hypersomnia?

Can menstrual cycles trigger hypersomnia episodes? Can taking hormones tame these symptoms? And does IH affect more women than men? We are delighted to have our Medical Advisory Board member Dr. Isabelle Arnulf, a Professor of Neurology at the Sorbonne University and one of the...

April 17, 2018

In All Hypersomnias, Ask the Doctor, Idiopathic Hypersomnia, Kleine-Levin Syndrome, Narcolepsy, Other Hypersomnias

By Hypersomnia Foundation

Ask the Doctor: What Is POTS, and What Does It Have to Do with Hypersomnia?

Although the Hypersomnia Foundation is not currently accepting new submissions for its Ask the Doctor series, we are working to answer previously submitted questions that are of general interest to our hypersomnia community. Today we have Dr. Mitchell Miglis of Stanford, a renowned expert in...

July 28, 2015

In All Hypersomnias, Clarithromycin, Idiopathic Hypersomnia, Journal Article Summaries, Kleine-Levin Syndrome, Narcolepsy, Other Hypersomnias, Treatments

By Hypersomnia Foundation

Antibiotic May Decrease EDS in GABA-Related Hypersomnia

A study of clarithromycin in the treatment of GABA-related hypersomnia indicates that this drug may be effective in some patients with idiopathic hypersomnia (IH), narcolepsy without cataplexy, and subjective hypersomnia. Background The US Food and Drug Administration (FDA) has not approved any drugs for the treatment of IH....

December 3, 2013

In All Hypersomnias, Clarithromycin, Idiopathic Hypersomnia, Journal Article Summaries, Kleine-Levin Syndrome, Narcolepsy, Other Hypersomnias

By Hypersomnia Foundation

Summary of Research into Clarithromycin as a Hypersomnia Treatment

GABA is known to promote sleep and decreased consciousness, and many patients with CNS hypersomnia have been found to have endogenous GABA-A receptor hyper-reactivity. Flumazenil, a known GABA-A antagonist, has been shown to reduce symptoms in these patients, but its use may be impractical; therefore,...

How Does GABA Affect Hypersomnia? Part 2 of Our Video Series Explains!

What Is GABA? How Does It Affect Hypersomnia? A New Video Series Explains!

Ask the Doctor: Do Women’s Hormones Affect Their Hypersomnia?

Ask the Doctor: What Is POTS, and What Does It Have to Do with Hypersomnia?

Antibiotic May Decrease EDS in GABA-Related Hypersomnia

Summary of Research into Clarithromycin as a Hypersomnia Treatment

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