Why is this study important?
Type 1 narcolepsy (T1N) and idiopathic hypersomnia (IH) are both disorders of central hypersomnolence. Even though the International Classification of Sleep Disorders, third edition,
Who were the researchers?
Dr. Filardi and his colleagues were from the University of Bologna in Italy.
Who were the research subjects?
Thirty-nine patients with T1N who had never received medicine to treat their narcolepsy, 24 patients with IH who had never received medicine to treat their IH, and 30 age- and sex- matched healthy CS took part in the study. For seven days, they each wore an actigraph and kept sleep-wake diaries, in which they noted when they went to bed, went to sleep, woke up during the night, and took naps. All of the subjects with T1N were HLA DQB1*0602 positive, as were 4 subjects with IH.
What were the results of the study?
People with T1N and IH had similar levels of subjective daytime sleepiness (Epworth Sleepiness Scale [ESS] scores were 16.4 and 14.5, respectively); the control group did not have daytime sleepiness (ESS score, 4.47). All of the people in this study spent about the same amount of time in bed. The people with T1N slept significantly less than both people with IH and CS. This study included a number of other findings as well.
What were the authors’ conclusions?
The present study shows that actigraphic monitoring is a useful technique to objectively assess the features of sleep–wake profile of central disorders of hypersomnolence, with the main advantage of providing more naturalistic information.
Filardi M, Pizza F, Martoni M, Vandi S, Plazzi G, Natale V. Actigraphic assessment of sleep/wake behavior in central disorders of hypersomnolence.Sleep Med. 2015;16(1):126-130.