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Treatments

SomnusNooze Articles > Treatments


EMA Recommends Approval of Pitolisant for the Treatment of Narcolepsy

On November 20, 2015, the European Medicine Agency’s (EMA) Committee for Medicinal Products for Human Use (CHMP) recommended that Bioprojet Pharma's drug pitolisant (Wakix) be approved for the treatment of narcolepsy with or without cataplexy. In making its recommendation, the Committee reviewed data from four studies of pitolisant—two placebo-controlled...

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Antibiotic May Decrease EDS in GABA-Related Hypersomnia

A study of clarithromycin in the treatment of GABA-related hypersomnia indicates that this drug may be effective in some patients with idiopathic hypersomnia (IH), narcolepsy without cataplexy, and subjective hypersomnia. Background The US Food and Drug Administration (FDA) has not approved any drugs for the treatment of IH....

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Does Modafinil Improve Sleepiness in People with IH without Long Sleep Time?

Background In Europe, modafinil used to be available as a treatment for the excessive daytime sleepiness (EDS) associated with idiopathic hypersomnia (IH). However, in 2010, the European Medicines Agency (EMA, the equivalent of the Food and Drug Administration [FDA] in the United States) changed the labeling, and...

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