Medical Terminology

HLA DQB1*0602

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The HLA, or human leukocyte antigen, system or complex is the gene complex that encodes for proteins on the surface of white blood cells. These cell-surface proteins are responsible for regulating our immune systems and our ability to fight infection. The HLA gene complex resides within chromosome 6. Most people with type 1 narcolepsy carry the HLA-DQB1*0602 gene, and are thus referred to as being “HLA-DQB1*0602 positive.” (Note: people with type 2 narcolepsy [or narcolepsy without cataplexy] often do not carry this gene).