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Bupropion (Wellbutrin, Zyban, Forfivo, Aplenzin) is an antidepressant that is known to have wake-promoting effects. It is a norepinephrine-dopamine reuptake inhibitor (NDRI), unlike most other antidepressants which are selective serotonin reuptake inhibitor (SSRIs). It works by inhibiting the reabsorption of two important brain chemicals – norepinephrine and dopamine. Read more about bupropion at MedlinePlus.gov HERE and on HF’s Treatment web page HERE.

Wellbutrin, Zyban, Forfivo, Aplenzin

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