bupropion« Back to Glossary Index
Bupropion (Wellbutrin, Zyban, Forfivo, Aplenzin) is an antidepressant that is known to have wake-promoting effects. It is a norepinephrine-dopamine reuptake inhibitor (NDRI), unlike most other antidepressants which are selective serotonin reuptake inhibitor (SSRIs). It works by inhibiting the reabsorption of two important brain chemicals – norepinephrine and dopamine. Read more about bupropion at MedlinePlus.gov HERE and on HF’s Treatment web page HERE.