Medical Terminology

norepinephrine reuptake inhibitors (NRIs)

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NRIs (norepinephrine reuptake inhibitors) are medications that work by blocking the action of the norepinephrine transporter (NET). NRIs are commonly used to treat major depressive disorder (MDD), anxiety, panic disorder, narcolepsy, and ADHD. NRI medications approved for use in the U.S. include atomoxetine (Strattera). Although NRIs are sometimes noted to be selective NRIs, this term is not to be confused with SNRIs (serotonin and norepinephrine reuptake inhibitors).