Medical Terminology

serotonin-norepinephrine reuptake inhibitors (SNRIs)

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SNRIs (serotonin-norepinephrine reuptake inhibitors) are medications that block the reabsorption (reuptake) of the neurotransmitters serotonin and norepinephrine in the brain. Most SNRIs treat depression, anxiety and long-term pain (especially nerve pain). SNRIs approved for use in the U.S. include desvenlafaxine (Pristiq), duloxetine (Cymbalta) and Venlafaxine (Effexor XR).