Medical Terminology

selective serotonin reuptake inhibitors (SSRIs)

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SSRIs (selective serotonin reuptake inhibitors) work by limiting, rather than blocking, the serotonin transporter (SERT). Essentially they work by increasing the levels of serotonin in the brain. They are typically used to treat MDD and anxiety disorders. SSRI medications approved for use in the U.S. include fluoxetine (Prozac) and sertraline (Zoloft).