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SomnusNooze Topics - Journal Article Summaries
Background According to the Narcolepsy Network, although it affects more than 200,000 people in the US, narcolepsy is estimated to be undiagnosed or untreated in 75% of people with the disorder. This lack of recognition leads to delays in effective... read >
Can Actigraphy Help to Differentiate People with Narcolepsy from People with Idiopathic Hypersomnia?
Why is this study important? Type 1 narcolepsy (T1N) and idiopathic hypersomnia (IH) are both disorders of central hypersomnolence. Even though the International Classification of Sleep Disorders, third edition, includes a finding of 11 hours of sleep... read >
Background In Europe, modafinil used to be available as a treatment for the excessive daytime sleepiness (EDS) associated with idiopathic hypersomnia (IH). However, in 2010, the European Medicines Agency (EMA, the equivalent of the Food and Drug... read >
GABA is known to promote sleep and decreased consciousness, and many patients with CNS hypersomnia have been found to have endogenous GABA-A receptor hyper-reactivity. Flumazenil, a known GABA-A antagonist, has been shown to reduce symptoms in these... read >