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single nucleotide polymorphism [SNP]

single nucleotide polymorphism [SNP]

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A SNP is a DNA variation in which one nucleotide (the building block of DNA) differs from what is generally observed in the population. SNPs happen normally throughout a person’s DNA—usually about once in every 300 nucleotides. These variations are typically found in the DNA between genes. They can act as markers, helping scientists locate genes that are associated with a specific disease. When SNPs appear within a gene or in a regulatory region near a gene, they may play a more direct role in disease by affecting the function of a gene.

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