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Journal Article Summaries

SomnusNooze Articles > Research > Journal Article Summaries


Does Excessive Daytime Sleepiness Affect Children’s Pedestrian Safety?

Background Each year, approximately 30,000 children are unintentionally killed or injured while walking outside (typically within a half mile of their homes). Many factors—including children’s thinking and reasoning abilities, attention spans, reaction times, impulsiveness, and willingness to take risks—likely play a role. Excessive daytime sleepiness (EDS),...

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Antibiotic May Decrease EDS in GABA-Related Hypersomnia

A study of clarithromycin in the treatment of GABA-related hypersomnia indicates that this drug may be effective in some patients with idiopathic hypersomnia (IH), narcolepsy without cataplexy, and subjective hypersomnia. Background The US Food and Drug Administration (FDA) has not approved any drugs for the treatment of IH....

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It’s a Fine Line Between Type 2 Narcolepsy and Idiopathic Hypersomnia… and It’s Getting Even Finer

Researchers have provided more evidence that narcolepsy without cataplexy (Nw/oC ) and idiopathic hypersomnia (IH) without long sleep time (LST) look more alike on testing than do narcolepsy with cataplexy (NwC) and Nw/oC. This research was completed before the publication of the International Classification of Sleep Disorders...

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New Findings in a Large Well-defined Group of People with KLS

Background Kleine Levin syndrome (KLS) is a neuropsychiatric disease that affects about 1 in a million people. Symptoms include hypersomnia, confusion, derealization, hypersexuality, megaphagia, altered mood, and hallucinations that occur during recurrent episodes, with normal sleep, thinking, mood, and behavior between episodes. Most people who have KLS...

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Can Actigraphy Help to Differentiate People with Narcolepsy from People with Idiopathic Hypersomnia?

Why is this study important? Type 1 narcolepsy (T1N) and idiopathic hypersomnia (IH) are both disorders of central hypersomnolence. Even though the International Classification of Sleep Disorders, third edition, includes a finding of 11 hours of sleep during a 24-hour period (as measured by actigraphy for at least 7...

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Does Modafinil Improve Sleepiness in People with IH without Long Sleep Time?

Background In Europe, modafinil used to be available as a treatment for the excessive daytime sleepiness (EDS) associated with idiopathic hypersomnia (IH). However, in 2010, the European Medicines Agency (EMA, the equivalent of the Food and Drug Administration [FDA] in the United States) changed the labeling, and...

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