An article published on May 11, 2015, in U.S. News & World Report highlights the struggles of two women whose lives are challenged by idiopathic hypersomnia. They are, as reporter Anna Miller explains, “at the sandman’s beck and call.”
Set your DVRs, check it out live, or catch a sneak peak, but don’t miss this program on sleep and idiopathic hypersomnia on CNN! Dr. Sanjay Gupta not only undergoes a Multiple Sleep Latency Test at Emory Sleep Lab, but also discusses idiopathic hypersomnia and its treatment with Dr. David Rye and Danielle Hulshizer. This episode of Vital Signs will air live on Saturday, April 25, 2015, at 3:30 PM EDT and again on Saturday, May 9, 2015, at 3:30 pm, EDT on CNN. In the meantime, you can watch the segments online by clicking on the following links.
This episode of the Today Show, which originally aired on November 20, 2012, offers a glimpse into the sleep-filled life of Nicole Delien, a 17-year-old with Kleine-Levin syndrome, and provides an interview with the physician who diagnosed her disorder, Dr. Michael Rancurello.
In a paper published in the November 21, 2012, edition of Science Translational Medicine, Dr. David Rye and a team of researchers from Emory University announced their discovery of a substance in the cerebrospinal fluid of 32 people with idiopathic hypersomnia that may be responsible for their relentless need to sleep. For now, the researchers are simply referring to this substance as a somnogen (or sleep-producing agent), which appears to heighten the effect of GABA when tested in the laboratory. Seven of the research subjects with idiopathic hypersomnia subsequently received flumazenil under experimental conditions and experienced normal levels of alertness.
Rye DB, Bliwise DL, Parker K, et al. Modulation of vigilance in the primary hypersomnias by endogenous enhancement of GABAA receptors. Sci Transl Med. 2012 Nov 21;4(161):161ra151. The paper is available free of charge after registering on the AAAS web site.